
REJURAN Skin Rejuvenation Bangkok
Restore, repair and rejuvenate your skin from within with authentic REJURAN Polynucleotide (PN) treatments.
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REJURAN Healer (2cc) — starting from ฿11,999
Full-face skin rejuvenation
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REJURAN i (2cc) — starting from ฿14,999
Targeted rejuvenation for the delicate eye area

Current PROMOTION for Rejuran Healer
Face & Neck Special — 4cc for ฿19,999
REJURAN is an injectable polynucleotide (PN) treatment designed to improve overall skin quality rather than simply adding volume. It is used to support skin restoration and can help improve concerns such as fine lines, rough texture, reduced elasticity, dryness and dull-looking skin.
At The Cosmo Clinic in Bangkok, REJURAN treatments are performed by licensed physicians and individually planned according to your skin condition, treatment area and goals.
Key Highlights
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Polynucleotide skin treatment: Designed to support skin restoration and improve overall skin quality
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Two REJURAN options: REJURAN Healer for general facial rejuvenation and REJURAN i for the eye area
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Improves skin rather than adding volume: A different approach from conventional dermal filler
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Gradual, natural-looking change: Skin quality improves progressively rather than creating an immediate structural change
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Doctor-performed: Every REJURAN treatment at The Cosmo Clinic is performed by a licensed physician
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Minimal downtime: Temporary small bumps, redness, swelling or bruising can occur after injection
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Bangkok locations: Available following consultation at The Cosmo Clinic.
What Is REJURAN?
REJURAN is a South Korean injectable treatment manufactured by PharmaResearch. It contains highly purified polynucleotides, commonly referred to as PN.
Polynucleotides are long chains of nucleotides, the basic building blocks of DNA. When injected into the skin, PN products are used in aesthetic medicine to support the skin's natural repair and remodelling processes.
Rather than filling wrinkles by physically adding volume, REJURAN is primarily used to improve the condition and quality of the skin itself.
For this reason, it is often described as a skin rejuvenation treatment or skin booster, although its mechanism is different from conventional hyaluronic-acid skin boosters.
REJURAN may be considered by patients concerned about:
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Fine lines
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Crepey or thin-looking skin
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Reduced elasticity
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Rough skin texture
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Dull or tired-looking skin
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Dehydrated skin
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Early signs of skin ageing
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Skin quality around the eyes
How Does REJURAN Work?
REJURAN is injected into the dermal layer of the skin using a series of small injections.
The polynucleotides form a temporary supportive environment within the treated tissue and are believed to encourage processes involved in skin repair and remodelling.
Clinical research into injectable polynucleotides has reported improvements in measures including skin texture, elasticity, fine wrinkles and overall skin appearance.
Unlike dermal filler, REJURAN is not primarily intended to reshape facial features or replace significant lost volume. Instead, the goal is gradual improvement in the quality, texture and condition of the skin.
REJURAN Healer vs REJURAN i
Although both treatments use REJURAN polynucleotide technology, they are intended for different treatment areas.
REJURAN Healer
฿11,999
REJURAN Healer is the primary REJURAN treatment used for general facial skin rejuvenation.
It is suitable for patients who want to improve overall skin quality rather than significantly change facial volume or contour.
REJURAN Healer may help improve:
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Fine lines
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Skin elasticity
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Skin texture
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Hydration
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Dullness
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Early signs of ageing
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Overall skin smoothness and appearance
The treatment can be distributed across multiple areas of the face depending on your skin condition and your doctor's assessment.
REJURAN i
฿14,999
REJURAN i is specifically designed for treatment of the delicate skin around the eyes.
The skin in the eye area is considerably thinner than most other areas of the face and commonly develops fine lines, crepiness and loss of elasticity earlier.
REJURAN i may be used to improve:
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Fine lines around the eyes
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Crepey under-eye skin
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Reduced elasticity
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Dry or tired-looking skin
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Overall under-eye skin quality
REJURAN i is intended to improve the skin itself and should not be confused with tear-trough filler.
If significant under-eye hollowing or volume loss is present, your doctor may discuss whether another treatment would be more appropriate.
Benefits of REJURAN Treatment
1. Improves Overall Skin Quality
REJURAN focuses on the condition of the skin rather than simply changing facial shape.
Treatment may help skin appear smoother, healthier and more refined over time.
2. Helps Improve Fine Lines
Improved skin quality and elasticity can soften the appearance of fine lines, particularly where ageing is associated with thinning or crepey skin.
3. Supports Skin Elasticity
Polynucleotide treatment is used to support dermal remodelling and may improve skin firmness and elasticity over a course of treatment.
4. Improves Skin Texture
REJURAN can be useful for patients whose primary concern is uneven, rough or ageing skin texture rather than volume loss.
5. Natural-Looking Results
Because REJURAN does not rely on adding significant facial volume, changes develop gradually.
The goal is for your skin to look healthier and better conditioned rather than noticeably "filled."
6. Suitable for Delicate Areas
REJURAN i provides an option specifically intended for the thin and sensitive skin surrounding the eyes, where conventional treatments may not always be suitable.
REJURAN vs Dermal Filler
REJURAN and dermal filler are injectable treatments, but they serve different purposes.
REJURAN primarily focuses on improving skin quality, texture, elasticity and fine lines.
Dermal filler is primarily used to restore or add volume, enhance facial contours or support areas affected by structural volume loss.
For example, a patient with thin, crepey under-eye skin may benefit from REJURAN i, while someone with a pronounced tear-trough hollow may require a different approach.
Some patients have both skin-quality concerns and volume loss. Your doctor can determine which treatment—or combination of treatments—is appropriate.
What to Expect During REJURAN Treatment
1. Consultation
Your appointment begins with an assessment by a licensed physician.
Your doctor will evaluate your skin, discuss your concerns and determine whether REJURAN Healer, REJURAN i or another treatment is most appropriate.
2. Preparation
The treatment area is cleansed thoroughly.
Topical anaesthetic cream may be applied before treatment to make the injections more comfortable.
Please tell your doctor about any medications, supplements, allergies or medical conditions before treatment.
3. Injection
REJURAN is administered using multiple small injections across the treatment area.
Treatment technique and injection pattern depend on the area being treated and your individual skin condition.
Small raised bumps are common immediately after treatment because small amounts of product are deposited within the skin.
These normally flatten gradually as the product disperses.
4. After Treatment
Temporary effects can include:
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Small injection bumps
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Redness
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Mild swelling
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Tenderness
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Bruising
These effects are generally temporary, although recovery varies between patients and treatment areas.
When Will I See Results From REJURAN?
REJURAN is not an instant-result treatment.
Some patients notice improvements in hydration or skin appearance relatively early, but changes in texture, elasticity and fine lines generally develop gradually as the skin responds to treatment.
Results are best assessed over the weeks following treatment rather than immediately after injection.
Because individual response varies, your doctor will recommend when your results should be reviewed.
How Many REJURAN Treatments Do I Need?
REJURAN can be performed as a single treatment, but patients seeking more significant skin-quality improvement may benefit from a course of treatments.
A treatment plan commonly involves several sessions spaced a few weeks apart, although there is no single protocol suitable for everyone.
The number and frequency of treatments will depend on:
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Your age
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Skin condition
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Treatment area
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Degree of skin ageing
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Previous treatments
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Your individual response
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Your desired result
Your doctor will recommend an appropriate schedule following assessment.
How Long Does REJURAN Last?
REJURAN gradually produces changes in skin quality rather than creating a temporary filling effect that disappears on a fixed date.
Clinical studies of polynucleotide skin treatments have reported improvements that remain measurable for several months after a treatment course.
How long you personally notice the benefits will depend on your age, skin condition, lifestyle, treatment course and natural ageing process.
Maintenance treatments may be recommended periodically for patients who want to continue supporting their results.
Who Should Consider REJURAN?
REJURAN may be suitable for adults who:
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Want to improve overall skin quality
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Have fine lines or early signs of ageing
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Have dry, dull or tired-looking skin
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Have reduced skin elasticity
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Want to improve skin texture
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Have thin or crepey skin around the eyes
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Prefer gradual, natural-looking improvement
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Do not necessarily require additional facial volume
REJURAN is not the correct treatment for every concern.
If your primary concern is significant skin laxity, deep wrinkles or volume loss, your doctor may recommend a different treatment.
Who Should Not Have REJURAN?
REJURAN may not be appropriate for patients who:
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Are pregnant or breastfeeding
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Have an active infection or inflammation in the planned treatment area
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Have a known allergy or hypersensitivity to ingredients in the product
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Have certain medical conditions affecting healing or immune function
Other medical conditions or medications may also affect your suitability for treatment.
Your medical history should always be discussed with your doctor before treatment.
Is REJURAN Safe?
REJURAN has been used internationally as a polynucleotide injectable treatment and published studies generally report a favourable tolerability profile.
However, all injectable medical treatments involve potential risks.
Common temporary effects include redness, swelling, tenderness, bruising and visible injection bumps.
More significant complications are uncommon but remain possible with any injectable procedure.
At The Cosmo Clinic, REJURAN treatment is performed by licensed physicians following individual medical assessment.
Why Choose The Cosmo Clinic for REJURAN in Bangkok?
1. Treatment by Licensed Physicians
REJURAN is an injectable medical treatment and every procedure at The Cosmo Clinic is performed by a licensed physician.
2. Genuine REJURAN Products
We use authentic REJURAN products manufactured by PharmaResearch.
Patients are welcome to ask to see the product packaging before treatment.
3. Individual Treatment Planning
Your doctor will assess your skin rather than automatically recommending the same treatment to every patient.
4. REJURAN Healer and REJURAN i Available
We offer both general facial rejuvenation with REJURAN Healer and specialised eye-area treatment with REJURAN i.
5. Transparent Pricing
REJURAN Healer — ฿11,999
REJURAN i — ฿14,999
Your treatment and price are discussed before the procedure begins.
6. English-Speaking Support
Our team regularly treats international patients in Bangkok and can explain your consultation, treatment plan, pricing and aftercare in English.
Combining REJURAN With Other Treatments
REJURAN can be used as a standalone skin-quality treatment.
Depending on your concerns, your doctor may also discuss other treatments that address different aspects of facial ageing.
REJURAN + Ultherapy PRIME
Ultherapy PRIME targets deeper tissue using microfocused ultrasound to improve lifting and tightening.
REJURAN focuses more superficially on skin quality.
For patients with both skin laxity and declining skin quality, the treatments may therefore address different concerns.
REJURAN + Botox
Botulinum toxin reduces movement in selected facial muscles to soften dynamic expression lines.
REJURAN works differently and is focused on improving the condition of the skin.
REJURAN + Dermal Filler
Dermal filler can restore facial volume and contour while REJURAN addresses skin quality.
The treatments may be complementary in patients experiencing both volume loss and changes in the skin itself.
Any combination treatment should be recommended according to your individual anatomy, concerns and treatment goals.
FAQs About REJURAN Treatment
Is REJURAN a filler?
REJURAN is an injectable product, but its main purpose is different from conventional hyaluronic-acid dermal fillers.
Traditional filler is generally used to create or restore volume and facial structure.
REJURAN is primarily used to improve skin quality and support tissue restoration rather than significantly changing facial volume.
What is the difference between REJURAN Healer and REJURAN i?
REJURAN Healer is used primarily for general facial skin rejuvenation.
REJURAN i is specifically intended for the thinner, more delicate skin around the eyes.
Your doctor can recommend the appropriate formulation based on the area you would like treated.
Does REJURAN hurt?
REJURAN requires multiple small injections, so some discomfort is expected.
Topical anaesthetic cream can be used before treatment to make the procedure more comfortable.
Patients commonly describe brief stinging or pinching during injection.
Is there downtime after REJURAN?
REJURAN generally requires little downtime, although small raised injection bumps, redness, mild swelling or bruising can occur.
The bumps usually settle as the product disperses into the skin.
We recommend allowing some recovery time before an important event, particularly if it is your first REJURAN treatment.
How soon will I see results?
REJURAN works gradually.
Some early improvement in the appearance or hydration of the skin may be noticeable, while changes in texture, elasticity and fine lines generally develop over the following weeks.
How long do REJURAN results last?
There is no single duration that applies to every patient.
Studies of polynucleotide skin rejuvenation have demonstrated improvements lasting for several months following treatment courses.
Your skin condition, age, lifestyle and treatment plan can all affect longevity.
Is REJURAN good for under-eye wrinkles?
REJURAN i is specifically designed for the delicate periocular area and may help improve fine lines, crepey texture and overall skin quality around the eyes.
It does not replace volume in the same way as tear-trough filler, so your doctor should first determine what is causing your under-eye concern.
How many REJURAN sessions should I have?
There is no mandatory number of treatments.
Some patients choose a single treatment while others undergo a course of several sessions to achieve greater improvement.
Your doctor will recommend a treatment schedule based on your skin and goals.
Is REJURAN the same as a hyaluronic acid skin booster?
No.
Both may be used to improve the appearance and quality of the skin, but they contain different materials and work through different mechanisms.
REJURAN uses polynucleotides, while many conventional injectable skin boosters are based primarily on hyaluronic acid.
